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Keytruda
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Decision Time Very Soon
Stopped abi. and started
Keytruda
(I am MSI- high, high TMB, MMR gene deficient) near end of June. PSMA PET showed about a dozen mets, all in bone, no organ or soft tissue. PSA at 1st infusion was 2.73, over 10 at 2nd and 18+ three weeks later.
Stopped abi. and started
Keytruda
(I am MSI- high, high TMB, MMR gene deficient) near end of June. PSMA PET showed about a dozen mets, all in bone, no organ or soft tissue. PSA at 1st infusion was 2.73, over 10 at 2nd and 18+ three weeks later.
rsgdmd
in
Advanced Prostate Cancer
9 months ago
In ICU for unstable blood pressure
Keytruda
side effect strikes again.
Keytruda
side effect strikes again.
GAdrummer
in
Advanced Prostate Cancer
8 months ago
is there any hope for me
full debunking surgery Chemo: carbo/taxol/avastin Jan 2020 avastin continued until April 2021 when reoccurrence Carbo/doxil from May to Nov. 2021 Olaparib until March 2022 Cisplatin and Gemzar April to Nov 22 Jan to May 2023 cancer spread from my lymph nodes to my liver and exploded cytotoxin,
Keytruda
full debunking surgery Chemo: carbo/taxol/avastin Jan 2020 avastin continued until April 2021 when reoccurrence Carbo/doxil from May to Nov. 2021 Olaparib until March 2022 Cisplatin and Gemzar April to Nov 22 Jan to May 2023 cancer spread from my lymph nodes to my liver and exploded cytotoxin,
Keytruda
Summergold2
in
My Ovacome
6 months ago
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Is HT Treatment necessary after Orchiectomey?
I did go for
Keytruda
, started it in March of 2022, but stopped in September because of pretty significant skin reaction. My PSA went from 3.31 in February 2022 to 0.09 3 months ago, so it definitely worked.
I did go for
Keytruda
, started it in March of 2022, but stopped in September because of pretty significant skin reaction. My PSA went from 3.31 in February 2022 to 0.09 3 months ago, so it definitely worked.
Bdale
in
Advanced Prostate Cancer
8 months ago
PLUVICTO
Note: I was diagnosed in September 2014 and I have had taxotere 6 rounds, Xtandi 2 years,
Keytruda
19 rounds and 12 rounds of taxotere prior to Pluvicto. I know many of you have suffered and been through a lot worse than I could imagine. I know I have had a good run.
Note: I was diagnosed in September 2014 and I have had taxotere 6 rounds, Xtandi 2 years,
Keytruda
19 rounds and 12 rounds of taxotere prior to Pluvicto. I know many of you have suffered and been through a lot worse than I could imagine. I know I have had a good run.
Jrb12
in
Advanced Prostate Cancer
9 months ago
Keynote 365 Trial
Hey fellas, Seeing my MO tomorrow about enrolling in the Keynote 365 clinical trial with
Keytruda
in combination with another drug. Has anybody had any experience with
Keytruda
? Did it work for you? SE’s?
Hey fellas, Seeing my MO tomorrow about enrolling in the Keynote 365 clinical trial with
Keytruda
in combination with another drug. Has anybody had any experience with
Keytruda
? Did it work for you? SE’s?
deano58
in
Advanced Prostate Cancer
4 months ago
Feeling very hopeless at this point.
He has been on doxetaxol, 2 times, zytiga, one clinical trial with
keytruda
, no result other than psa rising. Now on another clinical trial regeneron, now psa 571, scans were stable but now due again next week. On top of this, due to Xegeva, he has developed jaw necrosis.
He has been on doxetaxol, 2 times, zytiga, one clinical trial with
keytruda
, no result other than psa rising. Now on another clinical trial regeneron, now psa 571, scans were stable but now due again next week. On top of this, due to Xegeva, he has developed jaw necrosis.
Judymin
in
Advanced Prostate Cancer
8 months ago
Apheresis prior to starting Keytruda?
Will be starting
Keytruda
later this month and MO wants to do apheresis to collect T cells to freeze for possible CAR-T therapy in future, if
Keytruda
doesn't work well or issues with SEs.
Will be starting
Keytruda
later this month and MO wants to do apheresis to collect T cells to freeze for possible CAR-T therapy in future, if
Keytruda
doesn't work well or issues with SEs.
rsgdmd
in
Advanced Prostate Cancer
1 year ago
Update on Prostate Cancer Vaccines that I follow... another year is gone...
.: At this point, ADXS-PSA has not yet announced a Phase III trial, despite positive phase II results with
Keytruda
...
.: At this point, ADXS-PSA has not yet announced a Phase III trial, despite positive phase II results with
Keytruda
...
NPfisherman
in
Fight Prostate Cancer
7 months ago
Lung cancer and Keytruda
I was diagnosed with adenicarcinoma Stage 4, T1B, N3, M1B in January 2023 and offered Pembrolizumab (
Keytruda
) having a PD-LI expression of 50%. I have had 4 6-weekly cycles so far , with a CT scan after the first 2 sessions and I am due to have another in a couple of weeks - before I have cycle 5.
I was diagnosed with adenicarcinoma Stage 4, T1B, N3, M1B in January 2023 and offered Pembrolizumab (
Keytruda
) having a PD-LI expression of 50%. I have had 4 6-weekly cycles so far , with a CT scan after the first 2 sessions and I am due to have another in a couple of weeks - before I have cycle 5.
KipperKate
in
The Roy Castle Lung Cancer Foundation
11 months ago
CCR6 & CCL20 are the key drivers in prostate tumor microenvironment.
Surprisingly enough, drugs that can block CCL20 may also reduce autoimmune side-effects from standard PD-1 immunotherapy, such as Opdivo and
.
Surprisingly enough, drugs that can block CCL20 may also reduce autoimmune side-effects from standard PD-1 immunotherapy, such as Opdivo and
.
KocoPr
in
Fight Prostate Cancer
4 months ago
Starting Keytruda this week
Starting Keytuda on Tuesday, just shy of a year after 1st round of chemo. My profile has the details. I have MSI-high, high TMB, MMR mutations; only thing is PD-L1 is 1%, but very hopeful. Can any comment on side effects they had & when they showed up. How were they handled. I'm expecting fatigue, loss
Starting Keytuda on Tuesday, just shy of a year after 1st round of chemo. My profile has the details. I have MSI-high, high TMB, MMR mutations; only thing is PD-L1 is 1%, but very hopeful. Can any comment on side effects they had & when they showed up. How were they handled. I'm expecting fatigue, loss
rsgdmd
in
Advanced Prostate Cancer
11 months ago
I fired my oncologist
I also enrolled in a clinical trial of an experimental immunotherapy drug SD-101 along with infusions of
Keytruda
(pembrolizumab). I became extremely depressed, suicidal, lost all sex drive, sleeping 18 hours a day and sometimes entire days.
I also enrolled in a clinical trial of an experimental immunotherapy drug SD-101 along with infusions of
Keytruda
(pembrolizumab). I became extremely depressed, suicidal, lost all sex drive, sleeping 18 hours a day and sometimes entire days.
cageycruz
in
Advanced Prostate Cancer
11 months ago
Check Out the Latest on Keytruda Late Stage Phase 3 Trial Data!
Merk has announced that their drug
Keytruda
is at the end stages of their phase 3 trials and is a "smashing" success for triple negative, HR+ Metz, and early staged high risk patients as well. They are talking of "significant" survival as well as complete NED not only of tumors but free cells!!
Merk has announced that their drug
Keytruda
is at the end stages of their phase 3 trials and is a "smashing" success for triple negative, HR+ Metz, and early staged high risk patients as well. They are talking of "significant" survival as well as complete NED not only of tumors but free cells!!
Fiercefighter13
in
SHARE Metastatic Breast Cancer
10 months ago
Rechallenging with a previously failed treatment?
But, haven't heard about their possible benefit/success/failure except for a trial that failed for me using a triple combo of Actinium/
Keytruda
/Enzalutamide.
But, haven't heard about their possible benefit/success/failure except for a trial that failed for me using a triple combo of Actinium/
Keytruda
/Enzalutamide.
HopingForTheBest1
in
Advanced Prostate Cancer
11 months ago
Four Years Results
Shall I try vaccine first before starting
Keytruda
? Thank you very much my friends.
Shall I try vaccine first before starting
Keytruda
? Thank you very much my friends.
Pheart2
in
Advanced Prostate Cancer
11 months ago
What comes next?
So, I assume will be switched to enzalutemide & taper off steroid before starting
Keytruda
. Wondering if anyone has failed abi & had enzalutemide (or daralutemide) work for them? Thanks
So, I assume will be switched to enzalutemide & taper off steroid before starting
Keytruda
. Wondering if anyone has failed abi & had enzalutemide (or daralutemide) work for them? Thanks
rsgdmd
in
Advanced Prostate Cancer
1 year ago
Options after SOC have failed
I am starting
Keytruda
very soon and if it fails I will have exhausted all of my standard of care (SOC) options. Currently, I have lesions in a few lymph nodes in my abdominal and chest region that are continuing to show mild progression. Other than trials, what are our options beyond SOC?
I am starting
Keytruda
very soon and if it fails I will have exhausted all of my standard of care (SOC) options. Currently, I have lesions in a few lymph nodes in my abdominal and chest region that are continuing to show mild progression. Other than trials, what are our options beyond SOC?
Eddy-Merckx
in
Advanced Prostate Cancer
25 days ago
Cll to Hodgkins lymphoma
He has had 3 chemo treatments so far (AVD and
Keytruda
) every other week. He is now slowly gaining some weight back and working to regain some muscle by light exercise and some walking. This is going to be a long journey!
He has had 3 chemo treatments so far (AVD and
Keytruda
) every other week. He is now slowly gaining some weight back and working to regain some muscle by light exercise and some walking. This is going to be a long journey!
Junebug20
in
CLL Support
1 month ago
I need help with my attitude
I am waiting to find out if I qualify for a trial that compares
Keytruda
and Trodelvy against just trodelvy. I am waiting for liver biopsy to come back. I have been off of all meds for 2 weeks. My ascites has come roaring back.
I am waiting to find out if I qualify for a trial that compares
Keytruda
and Trodelvy against just trodelvy. I am waiting for liver biopsy to come back. I have been off of all meds for 2 weeks. My ascites has come roaring back.
Ticket123
in
SHARE Metastatic Breast Cancer
11 months ago
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