Ibrance/Femara cause of severe leg pain?

[Livetwentyyears]

Hi, I've been on Ibrance 100 & Femara 2.5 for 4 years, the problem I have is severe leg pain, had a lumpectomy 20 years ago, in 2015 it came back under my arm and collarbone. All pet scans good, no progression but I can barely walk, bone scan ok (8 mos. ago) my leg bone feels like my leg is gonna break as I am walking, I use a cane. I'm wondering if this can be from Ibrance or Femara? Any thoughts? Anyone else experience severe leg bone pain?

[Francesca10]

Please get

[Francesca10 in reply to Francesca10]

Please get it checked out. That doesn’t sound like it can wait.

[Livetwentyyears in reply to Francesca10]

Thank you, Im going to ask my primary for another bone scan. Nice to know you care!

[Red71]

How long has this been going on and have you talked to your oncologist about it yet? It doesn’t sound like something to be ignored!

[Livetwentyyears in reply to Red71]

It sure does sound like neuropathy, if it does get worse there are meds that help w/ nerve pain. I have neuropathy in my arm where they removed lymph nodes.As for me, another bone scan soon. Thanks and good luck Red 71!

[Mermaiden]

I’m sorry you are having such pain!! During the last six months I have experienced same - in my right knee, calf, foot, and strangely enough in my left hip. I have had it all checked out thoroughly and nothing definitive shows up to cause it. I now am pretty convinced it’s nerve pain, probably from a pinched nerve in my low back but I also suspect the meds (same) we are on contribute in a big way. My pain isn’t as bad lately, it waxes and wanes. I’m still in pursuit of answers and hope we can both find more relief!

[Felish48]

Hello Livetwentyyears,

I believe that it's the Ibrance/Letrozole, I'm experiencing the same thing. Most days I can't walk and it's annoying. I've also been experiencing increased back pain as well. I certainly hope that we both get some relief. God bless you...

[Safety1600]

Severe pain is serious. It could be a blood clot, which can occur with Ibrance. So to your doctor ASAP please!

[Felish48 in reply to Safety1600]

Ive been checked for blood clots 3 times .Thanks for the advice though.