Selecting the Correct Vitamin B12 Formula - Cure Parkinson's

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Selecting the Correct Vitamin B12 Formula

BoomMate112055 profile image
17 Replies

Selecting the Correct Vitamin B12 Formula ?

Hello Friends,

Are any of you taking vitamin B12 regularly, if so, which of the 4 main formulas are you taking.

This report has me interested in beginning a B12 supplement, I’m looking for help in choosing the right formula…someone much smarter than me will likely know, thanks in advance.

mayoclinicproceedings.org/a...

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BoomMate112055
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17 Replies
BoomMate112055 profile image
BoomMate112055

I think I answered my own question…this looks like the one…cyanocobamalin B12

Any feedback on this one is greatly appreciated.

CaseyInsights profile image
CaseyInsights in reply toBoomMate112055

Most knowledgeable people would choose methylcobalamin, as it easier for the body to utilize.

See here, though the writer for most part sits on the fence

healthline.com/nutrition/me...

BoomMate112055 profile image
BoomMate112055 in reply toCaseyInsights

Thanks Casey, I’ll have a look. 🙏🏻

LAJ12345 profile image
LAJ12345 in reply toBoomMate112055

the cyano one is the synthetic one they advise against. The methyl, adenosyl and possibly hydroxy are the ones you want

Smittybear7 profile image
Smittybear7

Interesting information. I work with a naturopath/pharmacist who has me talking B12-2000 twice a week. It also has B6 2mg, (pyridoxal-5-phosphate),and folate (as calcium pollinate 800mcg DFE.)

BoomMate112055 profile image
BoomMate112055 in reply toSmittybear7

I’ve been taking the P5P for a few weeks now…do you know the specific B12 formula you’re taking ?

Just to add to this topic, I’ve been taking Magnesium Glycinate and definitely notice a difference in my overall mood, I was taking Magnesium Oxide, don’t bother with the oxide…it’s useless

Thanks

Windermere1 profile image
Windermere1 in reply toBoomMate112055

oxide definitely useless. Cheap and nasty

Mirl profile image
Mirl in reply toSmittybear7

Very interessting. may i ask, do you benefit from it? I once read that a person with parkinson completely recovered from b12 injections. How long have you been taking that? Thanks for sharing

Shorebird profile image
Shorebird

We take Dr Mercola’s Methyl B12 energy boost - B12 as methylcobalamin- recommended by a friend who is a homeopathic provider.

jimcaster profile image
jimcaster

I take 3 capsules daily. Altogether, they amount to 1,500 mcg of methylcobalmin.

Picture of bottle
jackritchie47 profile image
jackritchie47

I would recommend Methylcobalamin as it is natural versus Cyanocobalamin which is synthetic. Methylcobalamin contains a methyl group which provides detoxification support. Cyanocobalamin contains a cyanide molecule which is not enough to kill a person, but why put that into your body. The gold standard is injectable methylcobalamin but you would need a prescription and have a compounding pharmacy (sterile) compound it. Next best absorbed format is sublingual tablets. Ortho Molecular Products makes a 5000mcg methylcobalamin + 1000mcg folate sublingual tablet... for once a day use. Swallow tablets are not well absorbed and are typically not recommended.

BoomMate112055 profile image
BoomMate112055

Thanks for all the feedback everyone, much appreciated !

jay_celine profile image
jay_celine

B12 was part of my daily regimen until I found negative posts like this just yesterday.

ncbi.nlm.nih.gov/pmc/articl...

There are other posts that discuss B12's possible link to lung cancer .

chartist profile image
chartist in reply tojay_celine

This March , 2023 study reached a different conclusion :

pubmed.ncbi.nlm.nih.gov/361...

Here is a relevant study quote :

' Vitamin B12 was not associated with lung cancer risk. In this sample of Chinese adults without confounding by unmetabolized folic acid, higher levels of 5-mTHF were associated with lower risk of incident lung cancer. '

Another consideration is that B12 deficiency can cause increased homocysteine and increased homocysteine can increase cancer risk as discussed here :

ncbi.nlm.nih.gov/pmc/articl....

Here is a relevant quote :

' One meta-analysis performed by Collin et al. demonstrated the relationship between blood total homocysteine and prostate cancer [21]. Another meta-analysis written by Xu et al. found that higher blood homocysteine levels increased gastric cancer risk [22]. '

A definite conundrum .

Art

Esperanto profile image
Esperanto in reply tojay_celine

A conundrum indeed. In any case you could conclude that it is wise to test your homocysteine level regular and recommended for a good interpretation to determine also vitamin B6, vitamin B12 and folic acid. Supplement only if really necessary.

Eddie129 profile image
Eddie129

does B12 in high doses have any side effects? I know if I take too much B1, I get jittery.

goldengrove profile image
goldengrove

I have the LRRK2 gene that makes it very likely I will develop PD if I live long enough. I was impressed by a study published in 2019 that showed in various animal models that the adenosyl form of B12 - adenosylcobalamin - inhibits the LRRK2 overactivity that is responsible for some genetic and some sporadic forms of PD.

I take 1 milligram of sublingual adenosyl cobalamin once or twice a week - the strawberry flavoured tablet contains 1000mcg (micrograms). I probably should take it more often. I believe absorption is much better from the mouth than swallowed - you place the tiny round tablet either under the tongue or tucked up between your teeth and cheek under the upper lip on either right or left side.

I don't think the study from Singapore about tiny differences in dietary B12 being correlated with higher rates of lung cancer is relevant - larger B12 intakes from diet would correlate with lots of confounders like higher red meat/eggs/animal protein and animal fat intake that could be the causal factor.

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