Can my mother take hemp oil tablets with Melat... - CLL Support

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Can my mother take hemp oil tablets with Melatonin to help her sleep whilst taking Ibrutinib?

MICHAELC74 profile image
11 Replies

My Mum struggles sleeping, she is also on I Ibrutinib. I recently bought her some hemp oil tablets with melatonin to see they helped her sleep. Is this ok with the chemo?

Many thanks

Michael C

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AussieNeil profile image
AussieNeilPartnerAdministrator

It's hard to say. I'm not sure what is in the hemp oil that purportedly helps with sleep, because the 'active' ingredients in CBD oil and hemp oil are different and there are good reasons to avoid CBD oil with Ibrutinib. That's because cannabinoids in CBD oil can both inhibit the enzyme in the liver that processes Ibrutinib, potentially worsening side effects, plus cannabinoids can directly counter the effect of Ibrutinib, causing CLL cells to relocate from the blood stream, back into the nodes. See:healthunlocked.com/cllsuppo...

healthline.com/health/hemp-...

and

healthunlocked.com/cllsuppo...

It may be that there is no adverse interaction, particularly if your mother takes her Ibrutinib in the morning, but why not just take Melatonin?

Neil

MICHAELC74 profile image
MICHAELC74 in reply toAussieNeil

Thanks for your reply Neil. It’s interesting to know that there is an interaction with CBD and ibrutinib. Makes me wonder if that could be the case with hemp oil tablets even though they are different to CBD

Provence profile image
Provence in reply toAussieNeil

Hello Neil, would you mind clarifying your last sentence because I don't understand it, in particular 'but not just Melatonin'. I myself take 5 mg of Melatonin every night because of a life time of sleeping problems. I take this 2 hours after I have taken the Ibrutinib tablet. So obviously I am interested in what you are saying here.

AussieNeil profile image
AussieNeilPartnerAdministrator in reply toProvence

I think I meant "but why not just take Melatonin?"

Provence profile image
Provence in reply toAussieNeil

Thanks for clarifying.

wmay13241 profile image
wmay13241

To calm down the horrible leg cramps caused by Ibrutinib, my wife takes doctor-prescribed oxycodone 5 mg tables - sometimes she takes 2 tablets for the cramps.

SofiaDeo profile image
SofiaDeo in reply towmay13241

Has she ever tried a far infrared heating pad? Mine has a temperature control that I can turn down so low there isn't really any heat, just far infrared (for summer). It helps me much more than drugs. And it's not just me-- I gave mine to try to a neighbor with CLL who hates taking pharmaceuticals & he loves it. Feet sore after a walk? Strained a muscle doing something? Having muscle spasms or cramps? It can help for lots of these issues.

Here's a very small study that indicates infrared heating pads may have helped people with chronic lower back pain. I say "indicates" because the study is too small to be statistically significant.

ncbi.nlm.nih.gov/pmc/articl...

And since the placebo effect comes into play, maybe it's just all in my head. But if it works for me, it works!

nccih.nih.gov/health/placeb...

health.harvard.edu/mental-h...

wmay13241 profile image
wmay13241 in reply toSofiaDeo

Thanks. I will ask her about it.

AnneHill profile image
AnneHill in reply towmay13241

My leg cramps were caused by low sodium. We dont use much salt these days but my levels were low. I put a bit on some foods but dont avoid it. Its stopped the cramp. I actually bought salted peanuts. Anne uk

Doremefasol profile image
Doremefasol in reply towmay13241

What kind of doctor it is? You could get addicted to opiates after 2 days use!

Eucalyptus22 profile image
Eucalyptus22

Instead of hemp I take a magnesium tablet at bedtime. It helps with both sleep and leg cramps. Apparently as we get older this is a supplement we should be taking as we don't process it well in the body as we age.

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